The Pawsey Supercomputing Centre


Evolution of the pentatricopeptide repeat (PPR) protein family in plants

The growth and development of living organisms is largely determined by the genes they contain, but converting the genetic information into biological activity requires intermediary processes involving ribonucleic acid (RNA) and proteins that bind to and process this RNA. This project aims to understand how the largest class of RNA-binding protein in plants recognise their target RNAs and will aid the development of custom-designed proteins for switching genes on or off at will. This technology will ultimately be used to create new hybrid cereal varieties and will also be valuable for applications in human health, such as the correction of genetic mutations.

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